The treatment for each patient is individualized and based on type and severity of symptoms.
Constipation-predominant IBS with mild symptoms may benefit from
- Increased fluid intake
- Guar gum
- Exercise
- Fiber
For constipation-predominant IBS with moderate symptoms,
- An antispasmodic (Bentyl)
- Peppermint oil
- Osmotic laxative
In severe cases, the above therapies may be supplemented with
- Tricyclic antidepressants
- Psychotherapy
- Consideration of drug like Paxil/lotronex
For diarrhea-predominant IBS, begin with
- Dietary changes
- Use an antispasmodic (Bentyl)
- Alternatively, peppermint oil if symptoms are moderate.
In severe diarrhea-predominant IBS,
- Consider tricyclic antidepressants
- Add a serotonin 5-HT3 antagonist (lotronex if patient is female).
In pain-predominant IBS
- Use an antispasmodic (Bentyl)
- Tricyclic antidepressant
If severe with diarrhea
- Consider a serotonin 5-HT3 agonist (lotronex).
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